The Single-Channel Electroporator is a state-of-the-art electroporation system designed for efficient delivery of RNP (Ribonucleoprotein) complexes and other nucleic acids into mammalian cells. This system enables precise control of electrical parameters, ensuring high transfection efficiency while maintaining excellent cell viability. Ideal for gene editing projects requiring consistent and reproducible results.
Product Code: LMAE-01
Advanced electroporation system designed for precise RNP delivery and electrotransfection processes in gene editing workflows
Real-world applications and results from our customers using Single-Channel Electroporator
Traditional viral transduction methods for CAR-T manufacturing faced high costs, lengthy production cycles, and regulatory complexity. The company needed a non-viral approach to deliver CRISPR RNP complexes for precise TCR knockout while maintaining high cell viability.
Implemented the Single-Channel Electroporator for RNP-based gene editing in primary T cells. Optimized electroporation parameters (voltage, pulse duration, pulse number) to achieve efficient CRISPR delivery while preserving T cell functionality and proliferation capacity.
The Single-Channel Electroporator transformed our CAR-T manufacturing process. We achieved reproducible high editing efficiency with excellent cell viability, significantly reducing both time and cost compared to viral methods.
Creating isogenic iPSC lines with precise gene modifications for disease modeling required high editing efficiency while maintaining pluripotency. Conventional electroporation systems caused significant cell death and loss of stem cell characteristics.
Utilized the Single-Channel Electroporator's precise control capabilities to deliver Cas9 RNP complexes into iPSCs. Fine-tuned electrical parameters to balance transfection efficiency with cell viability, followed by single-cell cloning to establish edited lines.
This electroporator enabled us to generate multiple isogenic iPSC lines with disease-relevant mutations in just 6 weeks. The high cell viability and preserved pluripotency were critical for our downstream differentiation experiments.
LMAE-02
LMAE-03